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SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization

Sulfur(VI) Fluoride Exchange (SuFEx) is a new family of click chemistry transformations which relies on readily available materials to produce compounds bearing the SVI—F motif. The potential of SuFEx in drug discovery has just started to be explored. We report the first method of SuFEx chemistry fo...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Liu, Zilei, Li, Jie, Li, Suhua, Li, Gencheng, Sharpless, K. Barry, Wu, Peng
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192542/
https://ncbi.nlm.nih.gov/pubmed/29451783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12788
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