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SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization

Sulfur(VI) Fluoride Exchange (SuFEx) is a new family of click chemistry transformations which relies on readily available materials to produce compounds bearing the SVI—F motif. The potential of SuFEx in drug discovery has just started to be explored. We report the first method of SuFEx chemistry fo...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Liu, Zilei, Li, Jie, Li, Suhua, Li, Gencheng, Sharpless, K. Barry, Wu, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192542/
https://ncbi.nlm.nih.gov/pubmed/29451783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12788
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