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SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization

Sulfur(VI) Fluoride Exchange (SuFEx) is a new family of click chemistry transformations which relies on readily available materials to produce compounds bearing the SVI—F motif. The potential of SuFEx in drug discovery has just started to be explored. We report the first method of SuFEx chemistry fo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Chem Soc
Egile Nagusiak: Liu, Zilei, Li, Jie, Li, Suhua, Li, Gencheng, Sharpless, K. Barry, Wu, Peng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192542/
https://ncbi.nlm.nih.gov/pubmed/29451783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12788
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