A Randomized Controlled Trial of Local Delivery of a Rho Inhibitor (VX-210) in Patients with Acute Traumatic Cervical Spinal Cord Injury

Acute traumatic spinal cord injury (SCI) can result in severe, lifelong neurological deficits. After SCI, Rho activation contributes to collapse of axonal growth cones, failure of axonal regeneration, and neuronal loss. This randomized, double-blind, placebo-controlled phase 2b/3 study evaluated the...

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Bibliografiset tiedot
Julkaisussa:J Neurotrauma
Päätekijät: Fehlings, Michael G., Chen, Yang, Aarabi, Bizhan, Ahmad, Faiz, Anderson, Kim D., Dumont, Travis, Fourney, Daryl R., Harrop, James S., Kim, Kee D., Kwon, Brian K., Lingam, Hari K., Rizzo, Marco, Shih, Ludy C., Tsai, Eve C., Vaccaro, Alexander, McKerracher, Lisa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc., publishers 2021
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Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8309435/
https://ncbi.nlm.nih.gov/pubmed/33559524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2020.7096
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