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Rho Signaling Pathway Targeted to Promote Spinal Cord Repair

The Rho signaling pathway regulates the cytoskeleton and motility and plays an important role in neuronal growth inhibition. Here we demonstrate that inactivation of Rho or its downstream target Rho-associated kinase (ROK) stimulated neurite growth in primary cells of cortical neurons plated on myel...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Dergham, Pauline, Ellezam, Benjamin, Essagian, Charles, Avedissian, Hovsep, Lubell, William D., McKerracher, Lisa
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758168/
https://ncbi.nlm.nih.gov/pubmed/12151536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-15-06570.2002
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