A Randomized Controlled Trial of Local Delivery of a Rho Inhibitor (VX-210) in Patients with Acute Traumatic Cervical Spinal Cord Injury

Acute traumatic spinal cord injury (SCI) can result in severe, lifelong neurological deficits. After SCI, Rho activation contributes to collapse of axonal growth cones, failure of axonal regeneration, and neuronal loss. This randomized, double-blind, placebo-controlled phase 2b/3 study evaluated the...

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Detalhes bibliográficos
Publicado no:J Neurotrauma
Main Authors: Fehlings, Michael G., Chen, Yang, Aarabi, Bizhan, Ahmad, Faiz, Anderson, Kim D., Dumont, Travis, Fourney, Daryl R., Harrop, James S., Kim, Kee D., Kwon, Brian K., Lingam, Hari K., Rizzo, Marco, Shih, Ludy C., Tsai, Eve C., Vaccaro, Alexander, McKerracher, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8309435/
https://ncbi.nlm.nih.gov/pubmed/33559524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2020.7096
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