An Effective and Safe Enkephalin Analog for Antinociception

Opioids account for 69,000 overdose deaths per annum worldwide and cause serious side effects. Safer analgesics are urgently needed. The endogenous opioid peptide Leu-Enkephalin (Leu-ENK) is ineffective when introduced peripherally due to poor stability and limited membrane permeability. We develope...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmaceutics
Prif Awduron: Viswanadham, K. K. DurgaRao, Böttger, Roland, Hohenwarter, Lukas, Nguyen, Anne, Rouhollahi, Elham, Smith, Alexander, Tsai, Yi-Hsuan, Chang, Yuan-Yu, Ortiz, Christopher Llynard, Yang, Lee-Wei, Jimenez, Liliana, Li, Siyuan, Hur, Chan, Li, Shyh-Dar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308721/
https://ncbi.nlm.nih.gov/pubmed/34206631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13070927
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