An Effective and Safe Enkephalin Analog for Antinociception

Opioids account for 69,000 overdose deaths per annum worldwide and cause serious side effects. Safer analgesics are urgently needed. The endogenous opioid peptide Leu-Enkephalin (Leu-ENK) is ineffective when introduced peripherally due to poor stability and limited membrane permeability. We develope...

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Publicado no:Pharmaceutics
Main Authors: Viswanadham, K. K. DurgaRao, Böttger, Roland, Hohenwarter, Lukas, Nguyen, Anne, Rouhollahi, Elham, Smith, Alexander, Tsai, Yi-Hsuan, Chang, Yuan-Yu, Ortiz, Christopher Llynard, Yang, Lee-Wei, Jimenez, Liliana, Li, Siyuan, Hur, Chan, Li, Shyh-Dar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308721/
https://ncbi.nlm.nih.gov/pubmed/34206631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13070927
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