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A cyclic enkephalin analog with high in vitro opiate activity.

A conformationally restricted analog of [Leu5]enkephalin was synthesized by cyclization of the COOH-terminal carboxyl group of leucine to the gamma-amino moiety of alpha, gamma-diaminobutyric acid (A2bu) substituted in position 2 of the peptide. Relative to [Leu5]enkephalin, the cyclic analog with D...

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Hlavní autoři: DiMaio, J, Schiller, P W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1980
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC350461/
https://ncbi.nlm.nih.gov/pubmed/6261242
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