Metformin and Niclosamide Synergistically Suppress Wnt and YAP in APC-Mutated Colorectal Cancer

SIMPLE SUMMARY: Hyperactivation of the canonical Wnt and inactivation of the Hippo pathway are well-known genetic backgrounds for familial adenomatosis polyposis (FAP) and colorectal cancer (CRC), although the reciprocal regulation between those pathways is not yet clear. In this study, we found tha...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Kang, Hee Eun, Seo, Yoojeong, Yun, Jun Seop, Song, Sang Hyun, Han, Dawool, Cho, Eunae Sandra, Cho, Sue Bean, Jeon, Yoon, Lee, Ho, Kim, Hyun Sil, Kang, Joyeon, Yook, Jong In, Kim, Nam Hee, Kim, Tae Il
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308039/
https://ncbi.nlm.nih.gov/pubmed/34298652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143437
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