Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner

Phosphorylation-dependent YAP translocation is a well-known intracellular mechanism of the Hippo pathway; however, the molecular effectors governing YAP cytoplasmic translocation remains undefined. Recent findings indicate that oncogenic YAP paradoxically suppresses Wnt activity. Here, we show that...

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發表在:Nat Commun
Main Authors: Lee, Yoonmi, Kim, Nam Hee, Cho, Eunae Sandra, Yang, Ji Hye, Cha, Yong Hoon, Kang, Hee Eun, Yun, Jun Seop, Cho, Sue Bean, Lee, Seon-Hyeong, Paclikova, Petra, Radaszkiewicz, Tomasz W., Bryja, Vitezslav, Kang, Chi Gu, Yuk, Young Soo, Cha, So Young, Kim, Soo-Youl, Kim, Hyun Sil, Yook, Jong In
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997650/
https://ncbi.nlm.nih.gov/pubmed/29895829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04757-w
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