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A Regulator Based “Semi-Targeted” Approach to Activate Silent Biosynthetic Gene Clusters

By culturing microorganisms under standard laboratory conditions, most biosynthetic gene clusters (BGCs) are not expressed, and thus, the products are not produced. To explore this biosynthetic potential, we developed a novel “semi-targeted” approach focusing on activating “silent” BGCs by concurren...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mingyar, Erik, Mühling, Lucas, Kulik, Andreas, Winkler, Anika, Wibberg, Daniel, Kalinowski, Jörn, Blin, Kai, Weber, Tilmann, Wohlleben, Wolfgang, Stegmann, Evi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306873/
https://ncbi.nlm.nih.gov/pubmed/34299187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147567
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