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Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters

Many drugs are derived from small molecules produced by microorganisms and plants, so-called natural products. Natural products have diverse chemical structures, but the biosynthetic pathways producing those compounds are often organized as biosynthetic gene clusters (BGCs) and follow a highly conse...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Brief Bioinform
Main Authors: Blin, Kai, Kim, Hyun Uk, Medema, Marnix H, Weber, Tilmann
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781578/
https://ncbi.nlm.nih.gov/pubmed/29112695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx146
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