Overproduction of Ristomycin A by Activation of a Silent Gene Cluster in Amycolatopsis japonicum MG417-CF17

The emergence of antibiotic-resistant pathogenic bacteria within the last decades is one reason for the urgent need for new antibacterial agents. A strategy to discover new anti-infective compounds is the evaluation of the genetic capacity of secondary metabolite producers and the activation of cryp...

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Bibliografiska uppgifter
Huvudupphovsmän: Spohn, Marius, Kirchner, Norbert, Kulik, Andreas, Jochim, Angelika, Wolf, Felix, Muenzer, Patrick, Borst, Oliver, Gross, Harald, Wohlleben, Wolfgang, Stegmann, Evi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Chemistry; Biosynthesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187939/
https://ncbi.nlm.nih.gov/pubmed/25114137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03512-14
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