A Regulator Based “Semi-Targeted” Approach to Activate Silent Biosynthetic Gene Clusters

By culturing microorganisms under standard laboratory conditions, most biosynthetic gene clusters (BGCs) are not expressed, and thus, the products are not produced. To explore this biosynthetic potential, we developed a novel “semi-targeted” approach focusing on activating “silent” BGCs by concurren...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Mingyar, Erik, Mühling, Lucas, Kulik, Andreas, Winkler, Anika, Wibberg, Daniel, Kalinowski, Jörn, Blin, Kai, Weber, Tilmann, Wohlleben, Wolfgang, Stegmann, Evi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306873/
https://ncbi.nlm.nih.gov/pubmed/34299187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147567
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