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Autophagy Inhibition in BRAF-Driven Cancers

SIMPLE SUMMARY: BRAF is a protein kinase that is frequently mutationally activated in cancer. Mutant BRAF can be pharmacologically inhibited, which in combination with blockade of its direct effector, MEK1/2, is an FDA-approved therapeutic strategy for several BRAF-mutated cancer patients, such as m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Foth, Mona, McMahon, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306561/
https://ncbi.nlm.nih.gov/pubmed/34298710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143498
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