AUY922 induces retinal toxicity through attenuating TRPM1

BACKGROUND: Ocular adverse events are common dose-limiting toxicities in cancer patients treated with HSP90 inhibitors, such as AUY922; however, the pathology and molecular mechanisms that mediate AUY922-induced retinal toxicity remain undescribed. METHODS: The impact of AUY922 on mouse retinas and...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Biomed Sci
Asıl Yazarlar: Shen, Che-Hung, Hsieh, Chi-Che, Jiang, Kuan-Ying, Lin, Chih-Yu, Chiang, Nai-Jung, Li, Ting-Wei, Yen, Chun-Ting, Chen, Wan-Ju, Hwang, Daw-Yang, Chen, Li-Tzong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306347/
https://ncbi.nlm.nih.gov/pubmed/34301262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00751-5
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller