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Reliability of Tumor Testing Compared to Germline Testing for Detecting BRCA1 and BRCA2 Mutations in Patients with Epithelial Ovarian Cancer

Background: BRCA 1/2 mutation status has become one of the most important parameters for treatment decision in patients with epithelial ovarian cancer (EOC). The aim of this study was to compare tumor DNA with blood DNA sequencing to evaluate the reliability of BRCA tumor testing results. Methods: P...

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Pubblicato in:J Pers Med
Autori principali: Bekos, Christine, Grimm, Christoph, Kranawetter, Marlene, Polterauer, Stephan, Oberndorfer, Felicitas, Tan, Yen, Müllauer, Leonhard, Singer, Christian F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305542/
https://ncbi.nlm.nih.gov/pubmed/34202525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11070593
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