Reliability of Tumor Testing Compared to Germline Testing for Detecting BRCA1 and BRCA2 Mutations in Patients with Epithelial Ovarian Cancer

Background: BRCA 1/2 mutation status has become one of the most important parameters for treatment decision in patients with epithelial ovarian cancer (EOC). The aim of this study was to compare tumor DNA with blood DNA sequencing to evaluate the reliability of BRCA tumor testing results. Methods: P...

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Publicado no:J Pers Med
Main Authors: Bekos, Christine, Grimm, Christoph, Kranawetter, Marlene, Polterauer, Stephan, Oberndorfer, Felicitas, Tan, Yen, Müllauer, Leonhard, Singer, Christian F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305542/
https://ncbi.nlm.nih.gov/pubmed/34202525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11070593
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