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The Role of Autophagy in Chemical Proteasome Inhibition Model of Retinal Degeneration

We recently demonstrated that chemical proteasome inhibition induced inner retinal degeneration, supporting the pivotal roles of the ubiquitin–proteasome system in retinal structural integrity maintenance. In this study, using beclin1-heterozygous (Becn1-Het) mice with autophagic dysfunction, we tes...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Gunawan, Merry, Low, Choonbing, Neo, Kurt, Yeo, Siawey, Ho, Candice, Barathi, Veluchamy A., Chan, Anita Sookyee, Sharif, Najam A., Kageyama, Masaaki
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303873/
https://ncbi.nlm.nih.gov/pubmed/34298888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147271
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