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The Role of Autophagy in Chemical Proteasome Inhibition Model of Retinal Degeneration

We recently demonstrated that chemical proteasome inhibition induced inner retinal degeneration, supporting the pivotal roles of the ubiquitin–proteasome system in retinal structural integrity maintenance. In this study, using beclin1-heterozygous (Becn1-Het) mice with autophagic dysfunction, we tes...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gunawan, Merry, Low, Choonbing, Neo, Kurt, Yeo, Siawey, Ho, Candice, Barathi, Veluchamy A., Chan, Anita Sookyee, Sharif, Najam A., Kageyama, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303873/
https://ncbi.nlm.nih.gov/pubmed/34298888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147271
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