Spermidine Oxidation-Mediated Degeneration of Retinal Pigment Epithelium in Rats

Retinal pigment epithelium (RPE) degeneration is a crucial event in dry age-related macular degeneration and gyrate atrophy. The polyamine spermidine has been shown to induce RPE cell death in vitro. The present study aimed to establish a novel in vivo model of spermidine-induced RPE degeneration an...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Ohashi, Koji, Kageyama, Masaaki, Shinomiya, Katsuhiko, Fujita-Koyama, Yukie, Hirai, Shin-ichiro, Katsuta, Osamu, Nakamura, Masatsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359532/
https://ncbi.nlm.nih.gov/pubmed/28367269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4128061
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