2-Phenyl-APB-144-Induced Retinal Pigment Epithelium Degeneration and Its Underlying Mechanisms

Purpose: To investigate the efficacy of 2-phenyl-APB-144 (APB)-induced retinopathy in a rat model and its underlying mechanisms, with a particular focus on retinal pigment epithelium (RPE) degeneration. Methods: Electroretinograms (ERGs) were evaluated in APB-administered rats. In ARPE-19 cells, cat...

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Detalhes bibliográficos
Publicado no:J Ocul Pharmacol Ther
Main Authors: Hirai, Shin-ichiro, Kurashima, Hiroaki, Nakamura, Daisuke, Komatsu, Tomoko, Yasuda, Yuki, Habashita-Obata, Sayo, Ichikawa, Sanae, Katsuta, Osamu, Iwawaki, Takao, Kohno, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642833/
https://ncbi.nlm.nih.gov/pubmed/26313169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2014.0076
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