Rational construction of genome-reduced Burkholderiales chassis facilitates efficient heterologous production of natural products from proteobacteria

Heterologous expression of biosynthetic gene clusters (BGCs) avails yield improvements and mining of natural products, but it is limited by lacking of more efficient Gram-negative chassis. The proteobacterium Schlegelella brevitalea DSM 7029 exhibits potential for heterologous BGC expression, but it...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Jiaqi, Zhou, Haibo, Yang, Zhiyu, Wang, Xue, Chen, Hanna, Zhong, Lin, Zheng, Wentao, Niu, Weijing, Wang, Sen, Ren, Xiangmei, Zhong, Guannan, Wang, Yan, Ding, Xiaoming, Müller, Rolf, Zhang, Youming, Bian, Xiaoying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302735/
https://ncbi.nlm.nih.gov/pubmed/34301933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24645-0
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