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Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species
Bacterial genomes encode numerous cryptic biosynthetic gene clusters (BGCs) that represent a largely untapped source of drugs or pesticides. Mining of the cryptic products is limited by the unavailability of streamlined genetic tools in native producers. Precise genome engineering using bacteriophag...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5939090/ https://ncbi.nlm.nih.gov/pubmed/29666226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720941115 |
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