Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species

Bacterial genomes encode numerous cryptic biosynthetic gene clusters (BGCs) that represent a largely untapped source of drugs or pesticides. Mining of the cryptic products is limited by the unavailability of streamlined genetic tools in native producers. Precise genome engineering using bacteriophag...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wang, Xue, Zhou, Haibo, Chen, Hanna, Jing, Xiaoshu, Zheng, Wentao, Li, Ruijuan, Sun, Tao, Liu, Jiaqi, Fu, Jun, Huo, Liujie, Li, Yue-zhong, Shen, Yuemao, Ding, Xiaoming, Müller, Rolf, Bian, Xiaoying, Zhang, Youming
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939090/
https://ncbi.nlm.nih.gov/pubmed/29666226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720941115
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi