Heterologous redox partners supporting the efficient catalysis of epothilone B biosynthesis by EpoK in Schlegelella brevitalea

BACKGROUND: Epothilone B is a natural product that stabilizes microtubules, similar to paclitaxel (Taxol); therefore, epothilone B and several derivatives have shown obvious antitumour activities. Some of these products are in clinical trials, and one (ixabepilone, BMS) is already on the market, hav...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Microb Cell Fact
Egile Nagusiak: Liang, Junheng, Wang, Huimin, Bian, Xiaoying, Zhang, Youming, Zhao, Guoping, Ding, Xiaoming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493146/
https://ncbi.nlm.nih.gov/pubmed/32933531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01439-5
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