Initiating polyketide biosynthesis by on-line methyl esterification

Aurantinins (ARTs) are antibacterial polyketides featuring a unique 6/7/8/5-fused tetracyclic ring system and a triene side chain with a carboxyl terminus. Here we identify the art gene cluster and dissect ART’s C-methyl incorporation patterns to study its biosynthesis. During this process, an appar...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Li, Pengwei, Chen, Meng, Tang, Wei, Guo, Zhengyan, Zhang, Yuwei, Wang, Min, Horsman, Geoff P., Zhong, Jin, Lu, Zhaoxin, Chen, Yihua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302727/
https://ncbi.nlm.nih.gov/pubmed/34301953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24846-7
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