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Initiating polyketide biosynthesis by on-line methyl esterification
Aurantinins (ARTs) are antibacterial polyketides featuring a unique 6/7/8/5-fused tetracyclic ring system and a triene side chain with a carboxyl terminus. Here we identify the art gene cluster and dissect ART’s C-methyl incorporation patterns to study its biosynthesis. During this process, an appar...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8302727/ https://ncbi.nlm.nih.gov/pubmed/34301953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24846-7 |
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