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Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes
Enediynes are potent antitumor antibiotics that are classified as 9- or 10-membered according to the size of the enediyne core structure. However, almost nothing is known about enediyne core biosynthesis, and the determinants of 9- versus 10-membered enediyne core biosynthetic divergence remain elus...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895059/ https://ncbi.nlm.nih.gov/pubmed/20534556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003442107 |
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