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Iterative Type I Polyketide Synthases for Enediyne Core Biosynthesis
Enediyne natural products are extremely potent antitumor antibiotics with a remarkable core structure consisting of two acetylenic groups conjugated to a double bond within either a 9- or 10-membered ring. Biosynthesis of this fascinating scaffold is catalyzed in part by an unusual iterative type I...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6312384/ https://ncbi.nlm.nih.gov/pubmed/19362637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(09)04605-9 |
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