Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival

Leiomyosarcomas (LMS) are genetically heterogeneous tumors differentiating along smooth muscle lines. Currently, LMS treatment is not informed by molecular subtyping and is associated with highly variable survival. While disease site continues to dictate clinical management, the contribution of gene...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nat Commun
المؤلفون الرئيسيون: Anderson, Nathaniel D., Babichev, Yael, Fuligni, Fabio, Comitani, Federico, Layeghifard, Mehdi, Venier, Rosemarie E., Dentro, Stefan C., Maheshwari, Anant, Guram, Sheena, Wunker, Claire, Thompson, J. Drew, Yuki, Kyoko E., Hou, Huayun, Zatzman, Matthew, Light, Nicholas, Bernardini, Marcus Q., Wunder, Jay S., Andrulis, Irene L., Ferguson, Peter, Razak, Albiruni R. Abdul, Swallow, Carol J., Dowling, James J., Al-Awar, Rima S., Marcellus, Richard, Rouzbahman, Marjan, Gerstung, Moritz, Durocher, Daniel, Alexandrov, Ludmil B., Dickson, Brendan C., Gladdy, Rebecca A., Shlien, Adam
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group UK 2021
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302638/
https://ncbi.nlm.nih.gov/pubmed/34301934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24677-6
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