Development of Genetically Flexible Mouse Models of Sarcoma Using RCAS-TVA Mediated Gene Delivery

Sarcomas are a heterogeneous group of mesenchymal malignancies and unfortunately there are limited functional genomics platforms to assess the molecular pathways contributing to sarcomagenesis. Thus, novel model systems are needed to validate which genes should be targeted for therapeutic interventi...

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Main Authors: Kabaroff, Leah, Gupta, Amar, Menezes, Serena, Babichev, Yael, Kandel, Rita C., Swallow, Carol J., Dickson, Brendan C., Gladdy, Rebecca A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986235/
https://ncbi.nlm.nih.gov/pubmed/24733554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094817
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