Signal strength controls the rate of polarization within CTLs during killing

Cytotoxic T lymphocytes (CTLs) are key effector cells in the immune response against viruses and cancers, killing targets with high precision. Target cell recognition by CTL triggers rapid polarization of intracellular organelles toward the synapse formed with the target cell, delivering cytolytic g...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Frazer, Gordon L., Gawden-Bone, Christian M., Dieckmann, Nele M.G., Asano, Yukako, Griffiths, Gillian M.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302442/
https://ncbi.nlm.nih.gov/pubmed/34292303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202104093
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