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Signal strength controls the rate of polarization within CTLs during killing

Cytotoxic T lymphocytes (CTLs) are key effector cells in the immune response against viruses and cancers, killing targets with high precision. Target cell recognition by CTL triggers rapid polarization of intracellular organelles toward the synapse formed with the target cell, delivering cytolytic g...

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Podrobná bibliografie
Vydáno v:J Cell Biol
Hlavní autoři: Frazer, Gordon L., Gawden-Bone, Christian M., Dieckmann, Nele M.G., Asano, Yukako, Griffiths, Gillian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302442/
https://ncbi.nlm.nih.gov/pubmed/34292303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202104093
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