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Fas Ligand localizes to intraluminal vesicles within NK cell cytolytic granules and is enriched at the immune synapse
INTRODUCTION: T cell and NK cell cytotoxicity can be mediated via the perforin/granzyme system and Fas Ligand (FasL, CD178). FasL is synthesized as a type II transmembrane protein that binds its cognate receptor Fas (CD95). Membrane‐bound FasL is expressed on the plasma membrane of activated lymphoc...
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| Vydáno v: | Immun Inflamm Dis |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5946154/ https://ncbi.nlm.nih.gov/pubmed/29642281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.219 |
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