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Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of Vixotrigine in Healthy Volunteers

Neuropathic pain affects ~ 6.9–10% of the general population and leads to loss of function, anxiety, depression, sleep disturbance, and impaired cognition. Here, we report the safety, tolerability, and pharmacokinetics of a voltage‐dependent and use‐dependent sodium channel blocker, vixotrigine, cur...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Naik, Himanshu, Steiner, Deb J., Versavel, Mark, Palmer, Joanne, Fong, Regan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301589/
https://ncbi.nlm.nih.gov/pubmed/33278330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12935
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