Repeated dosing with donepezil does not affect the safety, tolerability or pharmacokinetics of single-dose thioridazine in young volunteers

AIM: To investigate the effects of donepezil at steady state on the safety, tolerability and pharmacokinetics of a single dose of thioridazine, in healthy subjects. METHODS: An open, two-way, balanced crossover study, in 12 subjects (six men and six women) aged 19–41 years. During both treatment per...

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Detalhes bibliográficos
Main Authors: Ravic, Miroslav, Warrington, Steve, Boyce, Malcolm, Dunn, Kate, Johnston, Atholl
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
The clinical pharmacokinetics and safety of donepezil: an update Guest Editors: Stephen Jackson & Roy Jones
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884551/
https://ncbi.nlm.nih.gov/pubmed/15496221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.01800.x
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