Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function

The frequencies of genetic variants in the CYP3A4 and CYP3A5 genes differ greatly across global populations, leading to profound differences in the metabolic activity of these enzymes and resulting drug metabolism rates, with important consequences for therapeutic safety and efficacy. Yet, the impac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Transl Sci
Prif Awduron: Fohner, Alison E., Dalton, Rachel, Skagen, Kasse, Jackson, Konner, Claw, Katrina G., Hopkins, Scarlett E., Robinson, Renee, Khan, Burhan A., Prasad, Bhagwat, Schuetz, Erin G., Nickerson, Deborah A., Thornton, Timothy A., Dillard, Denise A., Boyer, Bert B., Thummel, Kenneth E., Woodahl, Erica L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2021
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301563/
https://ncbi.nlm.nih.gov/pubmed/33503331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12970
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg