Impact of pretreatment dihydropyrimidine dehydrogenase genotype‐guided fluoropyrimidine dosing on chemotherapy associated adverse events

Consensus guidelines exist for genotype‐guided fluoropyrimidine dosing based on variation in the gene dihydropyrimidine dehydrogenase (DPYD). However, these guidelines have not been widely implemented in North America and most studies of pretreatment DPYD screening have been conducted in Europe. Giv...

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Veröffentlicht in:Clin Transl Sci
Hauptverfasser: Wigle, Theodore J., Povitz, Brandi L., Medwid, Samantha, Teft, Wendy A., Legan, Robin M., Lenehan, John, Nevison, Stephanie, Panuganty, Veera, Keller, Denise, Mailloux, Jaymie, Siebring, Victoria, Sarma, Sisira, Choi, Yun‐hee, Welch, Stephen, Winquist, Eric, Schwarz, Ute I., Kim, Richard B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301551/
https://ncbi.nlm.nih.gov/pubmed/33620159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12981
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