Impact of pretreatment dihydropyrimidine dehydrogenase genotype‐guided fluoropyrimidine dosing on chemotherapy associated adverse events

Consensus guidelines exist for genotype‐guided fluoropyrimidine dosing based on variation in the gene dihydropyrimidine dehydrogenase (DPYD). However, these guidelines have not been widely implemented in North America and most studies of pretreatment DPYD screening have been conducted in Europe. Giv...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Wigle, Theodore J., Povitz, Brandi L., Medwid, Samantha, Teft, Wendy A., Legan, Robin M., Lenehan, John, Nevison, Stephanie, Panuganty, Veera, Keller, Denise, Mailloux, Jaymie, Siebring, Victoria, Sarma, Sisira, Choi, Yun‐hee, Welch, Stephen, Winquist, Eric, Schwarz, Ute I., Kim, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301551/
https://ncbi.nlm.nih.gov/pubmed/33620159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12981
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