Impact of pretreatment dihydropyrimidine dehydrogenase genotype‐guided fluoropyrimidine dosing on chemotherapy associated adverse events

Consensus guidelines exist for genotype‐guided fluoropyrimidine dosing based on variation in the gene dihydropyrimidine dehydrogenase (DPYD). However, these guidelines have not been widely implemented in North America and most studies of pretreatment DPYD screening have been conducted in Europe. Giv...

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Publicat a:Clin Transl Sci
Autors principals: Wigle, Theodore J., Povitz, Brandi L., Medwid, Samantha, Teft, Wendy A., Legan, Robin M., Lenehan, John, Nevison, Stephanie, Panuganty, Veera, Keller, Denise, Mailloux, Jaymie, Siebring, Victoria, Sarma, Sisira, Choi, Yun‐hee, Welch, Stephen, Winquist, Eric, Schwarz, Ute I., Kim, Richard B.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301551/
https://ncbi.nlm.nih.gov/pubmed/33620159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12981
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