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Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome

Dravet Syndrome (DS) is a severe childhood epilepsy caused by heterozygous loss-of-function mutations in the SCN1A gene encoding brain type-I voltage-gated sodium channel Na(v)1.1. DS is a devastating disease that typically begins at six to nine months of age. Symptoms include recurrent intractable...

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Detalhes bibliográficos
Publicado no:J Exp Neurol
Main Authors: Chuang, Shu-Hui, Westenbroek, Ruth E., Stella, Nephi, Catterall, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301289/
https://ncbi.nlm.nih.gov/pubmed/34308420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33696/neurol.2.040
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