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Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome
Haploinsufficiency of the voltage-gated sodium channel Na(V)1.1 causes Dravet syndrome, an intractable developmental epilepsy syndrome with seizure onset in the first year of life. Specific heterozygous deletion of Na(V)1.1 in forebrain GABAergic-inhibitory neurons is sufficient to cause all the man...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121787/ https://ncbi.nlm.nih.gov/pubmed/25024183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411131111 |
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