A Novel cis Regulatory Element Regulates Human XIST in a CTCF-Dependent Manner

The long noncoding RNA XIST is the master regulator for the process of X chromosome inactivation (XCI) in mammalian females. Here, we report the existence of a hitherto-uncharacterized cis regulatory element (cRE) within the first exon of human XIST, which determines the transcriptional status of XI...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Shah, Rini, Sharma, Ankita, Kelkar, Ashwin, Sengupta, Kundan, Galande, Sanjeev
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300786/
https://ncbi.nlm.nih.gov/pubmed/34060915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00382-20
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