Dynamic CTCF binding directly mediates interactions among cis-regulatory elements essential for hematopoiesis

While constitutive CCCTC-binding factor (CTCF)–binding sites are needed to maintain relatively invariant chromatin structures, such as topologically associating domains, the precise roles of CTCF to control cell-type–specific transcriptional regulation remain poorly explored. We examined CTCF occupa...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Qi, Qian, Cheng, Li, Tang, Xing, He, Yanghua, Li, Yichao, Yee, Tiffany, Shrestha, Dewan, Feng, Ruopeng, Xu, Peng, Zhou, Xin, Pruett-Miller, Shondra, Hardison, Ross C., Weiss, Mitchell J., Cheng, Yong
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2021
Assuntos:
Hematopoiesis and Stem Cells
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955410/
https://ncbi.nlm.nih.gov/pubmed/33512425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005780
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