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Unlinking a lncRNA from its associated cis element

Long non-coding (lnc) RNAs can regulate gene expression and protein functions. However, the proportion of lncRNAs with biological activities among the thousands expressed in mammalian cells is controversial. We studied Lockd (LncRNA downstream of Cdkn1b), a 434 nt polyadenylated lncRNA originating 4...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Paralkar, Vikram R., Taborda, Cristian C., Huang, Peng, Yao, Yu, Kossenkov, Andrew V., Prasad, Rishi, Luan, Jing, Davies, James O. J., Hughes, Jim R., Hardison, Ross C., Blobel, Gerd A., Weiss, Mitchell J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877494/
https://ncbi.nlm.nih.gov/pubmed/27041223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.02.029
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