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A Novel cis Regulatory Element Regulates Human XIST in a CTCF-Dependent Manner
The long noncoding RNA XIST is the master regulator for the process of X chromosome inactivation (XCI) in mammalian females. Here, we report the existence of a hitherto-uncharacterized cis regulatory element (cRE) within the first exon of human XIST, which determines the transcriptional status of XI...
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| 發表在: | Mol Cell Biol |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8300786/ https://ncbi.nlm.nih.gov/pubmed/34060915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00382-20 |
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