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Genetic mapping of novel modifiers for Apc(Min) induced intestinal polyps’ development using the genetic architecture power of the collaborative cross mice
BACKGROUND: Familial adenomatous polyposis is an inherited genetic disease, characterized by colorectal polyps. It is caused by inactivating mutations in the Adenomatous polyposis coli (Apc) gene. Mice carrying a nonsense mutation in the Apc gene at R850, which is designated Apc(Min/+) (Multiple int...
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| Publicat a: | BMC Genomics |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8299641/ https://ncbi.nlm.nih.gov/pubmed/34294033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07890-x |
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