Genetic mapping of novel modifiers for Apc(Min) induced intestinal polyps’ development using the genetic architecture power of the collaborative cross mice

BACKGROUND: Familial adenomatous polyposis is an inherited genetic disease, characterized by colorectal polyps. It is caused by inactivating mutations in the Adenomatous polyposis coli (Apc) gene. Mice carrying a nonsense mutation in the Apc gene at R850, which is designated Apc(Min/+) (Multiple int...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:BMC Genomics
Hlavní autoři: Dorman, Alexandra, Binenbaum, Ilona, Abu-Toamih Atamni, Hanifa J., Chatziioannou, Aristotelis, Tomlinson, Ian, Mott, Richard, Iraqi, Fuad A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299641/
https://ncbi.nlm.nih.gov/pubmed/34294033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07890-x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky