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Genetic mapping of novel modifiers for Apc(Min) induced intestinal polyps’ development using the genetic architecture power of the collaborative cross mice
BACKGROUND: Familial adenomatous polyposis is an inherited genetic disease, characterized by colorectal polyps. It is caused by inactivating mutations in the Adenomatous polyposis coli (Apc) gene. Mice carrying a nonsense mutation in the Apc gene at R850, which is designated Apc(Min/+) (Multiple int...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8299641/ https://ncbi.nlm.nih.gov/pubmed/34294033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07890-x |
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