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Container-aided integrative QTL and RNA-seq analysis of Collaborative Cross mice supports distinct sex-oriented molecular modes of response in obesity

BACKGROUND: The Collaborative Cross (CC) mouse population is a valuable resource to study the genetic basis of complex traits, such as obesity. Although the development of obesity is influenced by environmental factors, underlying genetic mechanisms play a crucial role in the response to these facto...

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Vydáno v:BMC Genomics
Hlavní autoři: Binenbaum, Ilona, Atamni, Hanifa Abu-Toamih, Fotakis, Georgios, Kontogianni, Georgia, Koutsandreas, Theodoros, Pilalis, Eleftherios, Mott, Richard, Himmelbauer, Heinz, Iraqi, Fuad A., Chatziioannou, Aristotelis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640698/
https://ncbi.nlm.nih.gov/pubmed/33143653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-07173-x
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