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Genetic analysis of intestinal polyp development in Collaborative Cross mice carrying the Apc(Min/+) mutation
BACKGROUND: Colorectal cancer is an abnormal tissue development in the colon or rectum. Most of CRCs develop due to somatic mutations, while only a small proportion is caused by inherited mutations. Familial adenomatous polyposis is an inherited genetic disease, which is characterized by colorectal...
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Publicado no: | BMC Genet |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761170/ https://ncbi.nlm.nih.gov/pubmed/26896154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0349-6 |
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