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Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
Cancer cells rewire their metabolism and rely on endogenous antioxidants to mitigate lethal oxidative damage to lipids. However, the metabolic processes which modulate the response to lipid peroxidation are poorly defined. Using genetic screens, we compared metabolic genes essential for proliferatio...
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| Publié dans: | Nat Chem Biol |
|---|---|
| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8299533/ https://ncbi.nlm.nih.gov/pubmed/32778843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0613-y |
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